Sarcoidosis patients on the MP have found that their depression lifted. This is probably due to their depression being caused by the major imbalance of hormones caused by elevated 1,25-D. Serotonin levels, for example, may be low because of this imbalance.
Dr. Marshall has created a diagram which summarizes some of the key relationships between the body's hormones and how they are affected by 1,25-dihydroxyvitamin-D. You can access it at http://autoimmunityresearch.org/hormones.pdf
The effect of sun/lights exposure during the summer and lack of sun/lights exposure during the winter can affect hormonal levels and, thus for some people, cause depression to wax and wane.
I never expected that my chronic, mild to moderate depression was a part of my disease or that it would be lifted by the MP. That is one of the very best things that has happened to me due to the MP and it only took about six months.
IMO, depression in persons with Th1 inflammatory disease is far more likely to be due to hormonal imbalance caused by dysregulated Vitmain D than SAD (seasonal affective disorder). I think the MP is worth a try for that reason alone.
Meg
Members' experiences
-the "Sparkle" is back. Now I don't feel depressed at all like I have in years past. no more SAD" ~DThomas
-Yep, my mood went way up as stress and anxiety went down. Felt like my brain had a big pressure load removed with the Benicar, and I mellowed right out. I have seen a number of people say that their moods improved tremendously when they started the Benicar. ~penny
-My mood improved seriously when I started wearing NoIRs, the most powerful antidepressivum I ever used. Did not start the benicar yet. The antidepressive effect of avoiding bright light is an impressive proof for 1,25D being involved in depression. ~Nightshade
-the "Sparkle" is back. Now I don't feel depressed at all like I have in years past. no more SAD. ~DThomas
* We can help you understand chronic disease, but only your physician is licensed to give you medical care * Always consult your physician before commencing or changing any treatment he/she has prescribed for you