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Vitamin D tests
 Moderated by: Dr Trevor Marshall  

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inge
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Joined: Mon Sep 25th, 2006
Location: Oslo, Norway
Posts: 163
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 Posted: Sat Sep 20th, 2008 13:54

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It is stated on the MP site that for vitamin D tests to be correct, the samples must be frozen before shipment to the lab. What is this based on? In this article vitamin D 1,25 is stable for at least 48 hours in room temperature:

The determination of 2β-(3-hydroxypropoxy)-1α,25-dihydroxy vitamin D3 (ED-71) in human serum by high-performance liquid chromatography-electrospray tandem mass spectrometry

Inge



____________________
CFS/ME 125D64 25D12(dec 07) Ph1De06 daily lite exp NoIR use Ph2Mar07 ModPh2 Jun07 abx brkOct 07 r//t KFTs freq abx chg to control kidney IP Apr 08 phase 2 abx
Dr Trevor Marshall
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 Posted: Sat Sep 20th, 2008 16:30

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Inge,
Most labs don't handle the samples properly, and a few will even process a 1,25-D sample which has been spoiled.

Quest labs is most reliable, and there is an FAQ covering this at
http://www.marshallprotocol.com/forum2/366.html
(look down the page for the letter from Elaine Phillips)

(Yes, I know Joe Mercola and the Vitamin D council are conducting an anti-Quest campaign right now. They are just plain wrong.)
 

Joyful
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Joined: Sat Jun 9th, 2007
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 Posted: Sat Sep 20th, 2008 20:49

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Hi Inge,

All the Quest 1,25D samples on the west coast of the USA are shipped to a particular Quest lab in San Juan Capistrano for analysis. This means the sample is always shipped.

And with the bright sun in the part of southern California, the box containing the sample would always be well heated in the delivery truck prior to receipt by the lab. Also, they may only run tests in batches once or twice a week depending on the number of samples coming in.

These are all good reasons for the handling instructions from Quest requiring the extra step of freezing the sample. :)

It turns out that my HMO (health maintenance organization), even with it's large enough size, ships all their 1,25D and 25D testing to this same Quest lab in San Juan Capistrano, so they must be known to 'specialize' in this area of testing.



____________________
Lyme Babs? Bart? | 125D50 Ph1Jul07 ModPh2Sep07 Ph2Feb08 Ph3Aug08 | cal/mag lysine hydroxyzine valium | rarely leave house NoIRs cover up low lux home | 25D15 Oct08
Rico
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 Posted: Sat Sep 20th, 2008 20:59

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What is it about Quest labs that Mercola and the Vit D council have issue with?



____________________
No diagnosis/some symptoms; wife with Sarc on MP; Olm 40mg q6h| avoid D| 1,25D=63 25D=32 (May 2006) 1,25D=44; 25D=10(Dec 2006)PhaseI(May06) PhaseII(Aug06) PhaseIII(Aug07)
benk
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Joined: Fri Dec 22nd, 2006
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 Posted: Sat Sep 20th, 2008 21:25

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Rico:
The Quest labs issue is at http://articles.mercola.com/sites/articles/archive/2008/09/20/warning-are-your-vitamin-d-test-results-valid.aspx?source=nl



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Lyme 125D77 Ph1Dec06 Avodart Cr picolinate vit B12 NoIRs low lux home fully covered if outdoors Ph3Feb07 25D8Mar08
Markt9452
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Joined: Sat Oct 27th, 2007
Location: Leamington, Ontario Canada
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 Posted: Sun Sep 21st, 2008 00:14

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The way I read that article is that all the clinical studies use the crap D test so we should all get the same crappy D test so that we are all talking about the same crap.:)
mt

Last edited on Sun Sep 21st, 2008 00:15 by Markt9452



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Th1 Inflammation Lyme vertigo fatigue brain fog skin lesions tinnitis 125D20 D2510 Ph1Feb08 Ph2Apr08 daily lite exp covered up NoIRs
Sunset
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 Posted: Mon Sep 29th, 2008 23:14

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I subscribe to Mercola's newsletter and for several months now I have consistently posted responses against his stand on vitamin D. In the articles he posts he tells people that Vitamin D via sun exposure is good for all. I have a standard response that I post on each article that refers people to the MP site; I note that while sun exposure may be ok for healthy people it is not healthy for anyone who has an inflammatory health condition. Yesterday I tried to post my standard response plus more information about Quest Diagnostics on the mercola.com site for Dr Mercola's most recent article that slanders Quest Diagnostics for handling the Vit D tests correctly (yes, that's basically what he is saying, although it sounds crazy). I'd like to note that while I did see other older posts from MP patient's defending the use of Quest Diagnostics along with explanations of the MP, my post has yet to show up on Mercola's site. In fact the last posted response to the article was on 9/20/08, nine days ago! I'm curious to know why Dr Mercola and his newsletter staff are censoring any further comments on the topic? Or, is it possible that this whole debate surrounding Vitamin D and chronic inflammatory diseases has reached a tipping point? Is it possible that Dr. Mercola has begun to re-evaluate his stance on Vitamin D. I suppose time will tell. I will be watching for any new articles he posts on the topic. This is the only reason I have continued to subscribe to his online newsletter. I use to value Dr. Mercola's medical opinions but now I question his motivation, after all he is making a lot of $$$ selling supplements and other items on his website....

Sunset



____________________
FM, CFS, migr HA, low adrenal, 11/07 tests 1,25D70, 25D48, 7/08 tests 25-D 21 ng/mL, olmesartan 40mg po & 20mg SL Q4H, milk thistle, NoIRs, limited lite exp, 22% zinc sunscreen,cover up.
garyv
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Joined: Thu Feb 14th, 2008
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 Posted: Tue Sep 30th, 2008 14:27

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Hi Sunset,

I can give you some background on Dr. Mercola. I've been banned (TWICE!) from his website due to my posts relating to the MP and, more specifically, due to my calling him on his deceitful behavior!

In March I first posted on his article at
 http://articles.mercola.com/sites/articles/archive/2008/03/08/is-vitamin-d-the-quot-nutrient-of-the-decade-quot.aspx where he recommends taking thousands of IU’s of D3 to achieve a 25(OH)D value of 50-55 ng/Ml (in his latest video he's now saying 65 ng/ML!!) specifically in order to prevent chronic AUTOIMMUNE diseases! He replied to my post, which simply related my honest experience with his “sunshine protocol” as well as a brief summary of Dr. Marshall’s work, as follows:

“Marshall's protocol is not new. It has been around for years. I have atended one of his seminars and am not impressed wth his data.” (misspellings left intact—might he have been a bit stressed?)

I then responded with the statistics for the various diseases from Joyce W’s 2-part article in the Townsend Letter last year. At the same time as Mercola’s response (I was refreshing the page occasionally, watching for replies), a -10 appeared on each of my 2-part posts, whereas other blog entries had only a few points, positive or negative. Realizing that this had to be the work of an administrator, I then posted again, calling him on this deceit:

“I honestly cited my own personal experience with your recommendations, which you apparently find so threatening that you slapped a -10 on both of my posts, fraudulently indicating to other readers that 10 people disapproved of my post. I know this was your doing since it appeared at the exact same time as your snippy, unhelpful retort.

“I have recommended your newsletter and website to family and friends for many years now and even defended you against other “big ego” alternative doctors such as Norman Shealy. It is truly disappointing to me to find that you seem to have “big ego” issues yourself and find it necessary to denigrate another’s experience in order to promote your own products and self-image.”

Well, that post stayed up for less than an hour, and I found my account banned from further posting, and all my posts (as well as Mercola’s comment) were removed! After a few days of thinking things over, I recalled an email offer to join Mercola’s “Inner Circle” where he sends you a hard-copy newsletter, DVD, and CD interview with an “expert” for the “bargain” price of $24.97/month. (Everything on his site is a “bargain,” no?) But you also get to comment on articles on his blog before he collects them for his 2x/week email newsletter. So I decided to join up! (and eagerly accepted, of course—obviously my money was not banned!)

In August I called up Customer Service and complained that I was unable to post on the blog, and eventually succeeded in getting my account reinstated. Just last Saturday when the article you mentioned http://articles.mercola.com/sites/articles/archive/2008/09/20/warning-are-your-vitamin-d-test-results-valid.aspx

appeared in Mercola’s newsletter, I made several posts and noticed that one in particular (which related my experience with having actually DONE the dual 25(OH)D test at Quest and LabCorp on the SAME DAY as recommended in the article) was being repeatedly removed within an hour or so of posting! (From the HTML source it appeared it was being marked as spam).

So I began reposting each time it happened and then noticed posts responding with favorable comments about the MP from OTHER bloggers being removed as well! I continued posting and responding to others with questions about the MP and noticed that one MD’s post questioning the value of D therapy had been rated a -29! The MD posted a reply indicating he planned to leave Mercola’s forum altogether, and then I posted this reply:

“Louis1, I feel certain your post was downrated 29 points due to a certain D r . You-Know-Who, since he did the same thing to one of my posts a couple of months ago. Having administrator privileges allows this sort of deceit to go on, so I can assure you that you were not downrated by other members of the community here but were singled out expressly because you are a practitioner who must be dissed because of your contrary opinion. At least your post wasn't deleted multiple times like Tilapia's and mine! 

“But please don't be intimidated and help us maintain our freedom of expression here--there are many people with chronic disorders who look to this site for advice (as I once did and still do for certain non-Vitamin D matters). We need to be here for them! Thanks again, Louis1, for your insights and for your courage in standing up for the truth of your experience!”

The next day I found my account banned again and all my posts deleted! So I simply opened another one with a different email address, and reposted (under username “rawtruth”) all 8 of the posts and replies I had earlier put there, except the one to the MD “Louis1” above. As of today, 7 of them have stuck, so it seems my persistence paid off!

But I think you can see what we’re up against! Mercola has his mind made up, apparently! But don’t give up—I told Gene Johnson what was going on, and he put up a post, which took some time to appear, but it eventually did. Since it was on Mercola’s blog that I first learned about the MP, I feel it’s my duty now to “pay it forward” to let other folks know about it, especially since Mercola influences a LOT of people--his is the top-rated alternative health site on the web.

Kind regards,
Gary



____________________
DxOsteoporosis/osteoarthritis/Raynauds/paresthesia/tinnitus 1,25D69 Ph1Mar08 Ph2Aug08 25D33(Oct08) no meds or light avoidance, covered in direct sunlight only
"Fear not the path of truth for the lack of people walking on it.” –Arabic proverb
Ron
Member in Phase 2


Joined: Mon Jan 7th, 2008
Location: Eindhoven, Netherlands
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 Posted: Tue Sep 30th, 2008 20:19

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Gary,

When I searched Mercola's site for "Marshall" on June 30 your posts still appeared in Google's cache. For some reason I decided to save that cache result to my harddrive, probably because of your vigorous response. :D

Anyway, it's now here.

Ron



____________________
Dad with RA, MP 01/08| 25D 16.8| Apr08 25D-7.1 Sept08 11.6| oxycodon, NoIRs, limited outings covered up
Sunset
Health Professional
 

Joined: Tue Oct 16th, 2007
Location: USA
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 Posted: Wed Oct 15th, 2008 00:48

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Hi Gary, I read Ron's cached copy of your post on Mercola's website and I am the person who you responded to at that website. I'm glad to see I reached at least one person.... :)

Here is copy of the most recent post I tried to send to Mercola's site in response to his article where he denounces Quest Diagnostics:

***********************************************************

Response to Dr Mercola’s Vit D labs post

Dr Mercola, you wrote:

"Although results from any of the three commonly used assays may be analytically accurate, they might not be clinically accurate, which is, ultimately, what matters..."

Dr Mercola, you are just plain wrong when you to tell people that a medical laboratory that handles a sensitive test for a potent hormone, 1, 25-D in an analytically correct manner is bad for the patient. Clinical accuracy means absolutely NOTHING if a sensitive hormone blood test is not properly handled in an ANALYTICALLY accurate manner. I would submit to you that the 1, 25-D lab test conducted by Quest Diagnostics provides patients, like me, who have an inflammatory health condition with the opportunity to receive proper treatment for their illness. I consistently tested low on the 25-D test despite plenty of sun exposure and supplementing with Vitamin D while at the same time I was experiencing symptoms of vitamin D toxicity. It was only when my doctor ordered the correct laboratory test for 1, 25-D through Quest labs that I realized I had hypervitiminosis, despite testing low for 25-D. A fundamental misconception in mainstream medicine today is the assumption that patients who suffer from inflammatory diseases handle the hormone “vitamin D” in their body in the same way as healthy people do; they do not. New scientific breakthroughs in the field of biochemistry offer a scientifically sound explanation for this type of hormone disregulation involved in inflammatory illnesses.

For signs of hypervitaminosis D check out http://www.marshallprotocol.com/forum2/2588.html

Once again, I strongly encourage all who suffer from an inflammatory health condition, conduct your own search on the website http://www.curemyth1.org and check out http://www.bateriality.com

If you have an inflammatory disease and wonder why you feel better in the summer, but worse in the winter check out http://www.marshallprotocol.com/forum32/1122.html


***********************************************************

Apparently I am one of those people now banned from posting on Dr Mercola's website as my above post never appeared on his site :?

I'm not religious be here's a few fitting Biblical quotes for Dr Mercola to ponder if he's lurking around on this site checking out what people really think about him...

“It is easier for a camel to go through the eye of a needle, than for a rich man to enter the kingdom of God” ... Dr. Mercola seems to sell a product on his website for every ailment, I suppose raking in $$$ on a very popular website is a good reason not to rock the boat and go against conventional medical practice.

"The truth shall set you free." ...Is there any hope that Dr. Mercola will finally see the error in his judgement and use this newly discovered information on Vit D to provide patients who have Th1 illnesses with sound medical advice on Vitamin D and their disease state?

“Great men are not always wise” ... Some advice for Dr. Mercola


Sunset :cool:



____________________
FM, CFS, migr HA, low adrenal, 11/07 tests 1,25D70, 25D48, 7/08 tests 25-D 21 ng/mL, olmesartan 40mg po & 20mg SL Q4H, milk thistle, NoIRs, limited lite exp, 22% zinc sunscreen,cover up.

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