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Dr Trevor Marshall Foundation Staff

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Posted: Thu May 31st, 2007 10:22 |
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There has just been some data on the canine version of the Cathelicidin anti-microbial peptides made available:
"Canine cathelicidin (K9CATH): Gene cloning, expression, and biochemical activity of a novel pro-myeloid antimicrobial peptide"
http://tinyurl.com/yuuwen PMID: 17462733
This joins the earlier paper:
"Molecular cloning and characterization of three beta-defensins from canine testes"
http://tinyurl.com/yp6aox PMID: 15845463
The data here cannot be directly applied to Homo sapiens, but does give a pretty good indication of what these peptides can do...
What I found surprising was the wide anti-microbial spectrum, and especially the activity of the beta-Defensins against Candida...
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wrotek Member in Phase 3

| Joined: | Fri Dec 31st, 2004 |
| Location: | Wroclaw, Poland |
| Posts: | 1174 |
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Posted: Sat Jun 2nd, 2007 05:35 |
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Is their mechanism of action bactericidal ? Do they kill CWD too ?
____________________ Lyme reflux chronic pain fatigue depression 125D36 Ph1Sep05 Ph2Oct06 Ph3Apr07 homebound in low lux NoIRs 25D<7 Oct06
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