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shandym
Member
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Posted: Wed Apr 30th, 2008 19:22 |
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Does the same thing apply for people who "gain" weight during illness?
I have always been thin, but since becoming ill I have put on a lot of weight and cannot take it off even when I barely eat.
I always though being as ill as I am that I would be "thin" or even thinner than I always have been.....Instead I am 50 pounds over weight now.
I hate it.  Last edited on Wed Apr 30th, 2008 19:23 by shandym
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FM like Pain, disequalibrium,vertigo, constant dizziness, palpitations, tachycardia, visual disturbances,headpressure/headpain 125D29, 25D7, MP 11/07, TUMS, Valium, NoIRs, limited outings covered up
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tickbite
Guests visiting Phase 1/2/3
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Posted: Wed Apr 30th, 2008 19:35 |
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I believe that is a yes. However, as Amy quoted Trevor about the level of uncertainty at the moment it isn't near the point of being understood. I'm sure some people are able to stabilize weight or weight loss with the use of Benicar, but others may not.
Amy,
Thanks for the link skinny girl! Provides some insight for sure. I guess I will continue with my mega huge calorie diet, knowing that some day i'll actually gain some weight and have to watch it  I think that situation will be better anyway because it seems that when I don't eat enough food I feel drained. I'd rather not have to continually eat like a cow and actually have fuel reserves.
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"Lyme","CFS", Meningitis
Phase3 8-2-07, MP on hold 11/2007
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bealunn
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Posted: Sun Oct 19th, 2008 18:58 |
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Two interesting articles on the BBC Health pages recently. Both relating to research into obesity and both linking this to inflamation and the immune system.
Obesity ‘lifts inflammation risk’
New twist in brain obesity riddle
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Sarcoidosis/lungs -25D 9(August07)/25D 4(July08)/25D 4(December08)/25D 5,3(October09) -Phase 1:May08-Phase 2:July08-Phase 3:Z+M+C Jan09 (max dosage Nov09)- NoIRs low lux home limited outings covered
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eClaire
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Posted: Fri Oct 24th, 2008 07:47 |
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I love these studies (NOT) that keep making one symptom be the cause of another symptom. Obesity causes blah, blah, blah, just like low Vit D causes blah, blah, blah.
My response to these "scientists": yada, yada, yada.
Claire
Last edited on Fri Oct 24th, 2008 07:48 by eClaire
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38mo on MP; CFS FMS MCS COPD hypermob. IBS/GERD osteopor.; 125D48 25D<4;
NoIRs during most daylight outings & covered up; home w/o NoIRs
Ph1.Dec06 * ModPh2.Jun07 * AbxBrk.Mar-May08 * Ph2.Oct-Nov08 * Ph1.Jan2009
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Karon
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Posted: Fri Oct 24th, 2008 16:27 |
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Thank you Claire  
you made my morning......long time and alot happening with no talk....I'm sorry.
I had a lot of BLAH BLAH YADA YADA to sift through. How are you besides my morning light today?
missing you today
Love to you Dear Claire
Karon
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LYME,PTSD,RA,CFS,ChronInflamDisease,
Depression/Anxiety
Naproxen/Tramadol/Valium/Flexiral/Otc sleepaid, PRN
|125D =73 25D=20(May08)| 25D=14.4(Jul08) 25D=14(June09)
[PH1-Apr08| [Ph2-Aug08] [Ph3-Apr09]
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eClaire
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Posted: Fri Oct 24th, 2008 23:59 |
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I'm glad you got a laugh. When you read the science news, if you're not laughing, you're bound to be crying most of the time. I picked this quotation up from the Lifestyles quotation thread and have it in my personal emails: "Man will occasionally stumble over the truth, but most of the time he will pick himself up and continue on." Winston Churchill
It seems when it comes to medical research, the truth can be staring folk right in the face and they make a big production of the detour they are taking instead. Least wise, they ought to be able to see that they are just making a bunch of hooey over a detour.
Claire
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38mo on MP; CFS FMS MCS COPD hypermob. IBS/GERD osteopor.; 125D48 25D<4;
NoIRs during most daylight outings & covered up; home w/o NoIRs
Ph1.Dec06 * ModPh2.Jun07 * AbxBrk.Mar-May08 * Ph2.Oct-Nov08 * Ph1.Jan2009
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Dr Trevor Marshall
Foundation Staff
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Posted: Sat Oct 25th, 2008 11:38 |
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Beatrice, have you had a chance to have a look at the videos of the Porto presentations? I think they will help you understand where our MP science is at the moment.
I have just got back from a conference on "Beneficial Microbes." I think you will be amazed to see the way that our microbial load changes the entire way that our body operates. The NIH estimates that only 10% of the cells in our body are human cells, and 90% are bacterial. Look here: http://nihroadmap.nih.gov/hmp/
The keynote presentation at the microbes conference was Jeremy Nicholson, head of Biological Chemistry at Imperial College, London. He reminded us all that pharmaceutical drugs work differently in different populations, and that various populations are indeed made different by the microbiota they carry. He believes that drugs tested in India and Romania are going to work quite differently when they are used in the US, UK and Western Europe. He believes this will spell disaster for Medicine, as we know it. All the work of tens of thousands of scientists, and hundreds of clinical trials, will be defeated by something nobody has noticed until now - the bugs we all carry around with us. Here is one of his slides:
This plots the urine metabolome of three nationalities, a snapshot of how all the bacterial metabolite products, they which excrete in their urine, maps onto a display space.
About 50 of these Japanese subjects moved to the USA, and they assumed the USA metabolome, you can see a few inside the mass of US subject data.
The whole world is changing, and much faster than anybody expected....
..Trevor..
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kenc
Member in Phase 3
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Posted: Mon Oct 27th, 2008 05:53 |
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Dr. Trevor Marshall,
What is the meaning of position on the display space in Jeremy Nicholson's slide? That is, how are the x and y axes defined?
Ken
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NickBowler
Member in Phase 3
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Posted: Wed Dec 10th, 2008 17:19 |
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http://www.newscientist.com/article/mg20026855.500-bug-genes-are-the-key-to-human-digestion.html
The authors seem to think that there is a need for some bacteria in the gut for optimal digestion, but what caught my eye was the differences they found between lean and obese people's gut bacteria.
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eClaire
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Posted: Wed Dec 10th, 2008 23:14 |
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I found this interesting b/c my brother and I came from a long line of slender (even thin) people and yet he was fat all his life and I struggled, and lost a few times (especially when I became disabled) from becoming fat. I seemed to share similar characteristics in regard to body type of my cousins and yet they and my parents could eat all they wanted and never have to worry about the weight. I obviously had the bacteria that was fond of carbohydrates.'
So we either inherited recessive genes or took on a lot of bacteria associated with obesity.
Claire
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38mo on MP; CFS FMS MCS COPD hypermob. IBS/GERD osteopor.; 125D48 25D<4;
NoIRs during most daylight outings & covered up; home w/o NoIRs
Ph1.Dec06 * ModPh2.Jun07 * AbxBrk.Mar-May08 * Ph2.Oct-Nov08 * Ph1.Jan2009
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Dr Trevor Marshall
Foundation Staff
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Posted: Wed Dec 10th, 2008 23:56 |
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Nick,
I should be putting my presentation(s) in China online sometime in the next week. Take a look at the slide illustrating how some gut-bacterial species can affect disease-related genes
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TikBitten
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Posted: Fri Dec 19th, 2008 10:30 |
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Dr. Marshall-
PLEAZZZEE reassure all Th1 patients that Benicar is still the root answer to all this bacterial evil.....
TB
p.s. Would seem changes in biology are not all that disimilar to wrenching changes in physics!!! From Feynman point particle theory to M-theory and non-euclidiean multi-dimensional space being unified by CMB data sets and the dodecahedron spacial measurements of NASA's WMAP satellite, incredible! Have physics, chemistry and biology begun to converged at all levels???
Last edited on Fri Dec 19th, 2008 11:00 by TikBitten
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Dx:Neurborreliosis 8/05|25D=46 1,25D=62 10/07|Avoid Sun&VitD since 10/07|Started Ph1&NoIRs 3/08|25D=18 3/08|25D=17 6/08|ModPh2 6/08|Ph2 9/08 stopped NoIRs|Ph3 1/09|25D=13 3/09|25D=10 5/09|25D=11 7/09|25D=15 9/09
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Dr Trevor Marshall
Foundation Staff
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Posted: Fri Dec 19th, 2008 10:36 |
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Reactivating the VDR is the way to defeat the Th1 microbiota, as it persists by blocking VDR gene transcription.
At the moment we use Benicar to reactivate the VDR and start transcribing the protective genes.
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TikBitten
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Posted: Fri Dec 19th, 2008 11:13 |
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Please bear with me...
How are Th1 microbiota differentiated from the trillions of harmless metagenomic gut microbes found in healthy individuals? Anything to do with Gram-negative vs Gram-postitive classification or is that history too?? But according to the graph above, of course, healthy indviduals must now be sub-classified by region as well...
NYC metro area,
TB
Last edited on Fri Dec 19th, 2008 11:17 by TikBitten
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Dx:Neurborreliosis 8/05|25D=46 1,25D=62 10/07|Avoid Sun&VitD since 10/07|Started Ph1&NoIRs 3/08|25D=18 3/08|25D=17 6/08|ModPh2 6/08|Ph2 9/08 stopped NoIRs|Ph3 1/09|25D=13 3/09|25D=10 5/09|25D=11 7/09|25D=15 9/09
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Dr Trevor Marshall
Foundation Staff
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Posted: Fri Dec 19th, 2008 11:16 |
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TikBitten wrote: How are Th1 microbiota differentiated from the trillions of harmless metagenomic gut microbes found in healthy individuals?
Are you sure those gut-microbes are harmless? My presentations dealt specifically with that issue. Video should be online within a few days.
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TikBitten
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Posted: Fri Dec 19th, 2008 11:25 |
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One more thought-
I was actually referring to Dr. Gordon's Nirvana (idealistic) state of beneficial gut microbial balance that yields optimal energy and nutritional benefits-- or is this another 20th century marketing micro-biochemical illusion too??
TB
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Dx:Neurborreliosis 8/05|25D=46 1,25D=62 10/07|Avoid Sun&VitD since 10/07|Started Ph1&NoIRs 3/08|25D=18 3/08|25D=17 6/08|ModPh2 6/08|Ph2 9/08 stopped NoIRs|Ph3 1/09|25D=13 3/09|25D=10 5/09|25D=11 7/09|25D=15 9/09
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Dr Trevor Marshall
Foundation Staff
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Posted: Fri Dec 19th, 2008 11:41 |
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The question is not only whether certain families of microbes can improve our absorption of gut nutrients, but whether there are any harmful effects from that symbiosis. Jeff's group is still some distance from pondering that question. I ponder it on slide 6 (or is it 5) of my China presentations
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TikBitten
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Posted: Fri Dec 19th, 2008 12:21 |
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| Looking forward to it...
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TikBitten
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Posted: Fri Dec 19th, 2008 12:26 |
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BTW-
What are the latest options for prescription (or non-prescription) sleep aids??
TB
Last edited on Fri Dec 19th, 2008 12:27 by TikBitten
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Dx:Neurborreliosis 8/05|25D=46 1,25D=62 10/07|Avoid Sun&VitD since 10/07|Started Ph1&NoIRs 3/08|25D=18 3/08|25D=17 6/08|ModPh2 6/08|Ph2 9/08 stopped NoIRs|Ph3 1/09|25D=13 3/09|25D=10 5/09|25D=11 7/09|25D=15 9/09
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goobygirl
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Posted: Sun Dec 21st, 2008 03:06 |
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I also question whether one of the reasons people gain weight is the type of food they eat, particularly, cooked v. raw. I forayed into raw food eating this fall and lost 7 lbs in 5 weeks, and took another 2 off since then simply by making two meals all raw. I wasn't fat to begin with, was in the middle of height and weight charts, and didn't exercise other than the walking I normally do in a day. I was a vegetarian to begin with and had a diet most Americans never came close to as far as nutrients, IMO.
To me, it makes sense. No other "animal" cooks or heats its food. It seems to me that the body can more easily recognize, digest, and assimilate food that hasn't been messed with. The zebra eats its food as it finds it, as does the lion. The zebra doesn't steam his grass and the lion doesn't grill its zebra meat.
I'm keeping raw in my diet, I feel better on it, and it works for me.
Last edited on Sun Dec 21st, 2008 03:08 by goobygirl
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FM, Hashimoto's, sleep apnea, TMJ, endometriosis, migraines, carpal tunnel; initial testing: 125D 24.2 pg/ml, D25 - 33.5ng/ml; last test 12/6/09: 25D 8; mp began 11/07; 100 mcg Cytomel, 5 mg Valium as needed and for sleep.
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