Won't the bacteria become immune/resistant to the antibiotics if I take them a long time?
Ethics of withholding antibiotic treatment
"We now have very detailed knowledge of exactly how the MP antibiotics work, and, in my opinion, it is no longer ethical to keep patients suffering from chronic disease merely by bringing up 25 and 50 year old concepts of 'resistance' to try and cover-up one's lack of genomic knowledge. Medicine has the knowledge. We must all help medicine to use that knowledge and wipe out suffering from these chronic diseases." Dr. Trevor Marshall, Ph.D.
Bacterial resistance to minocycline
Doctors have, for years, prescribed minocycline for conditions such as acne at much higher doses than the Marshall Protocol. There is no indication that intracellular bacteria can become resistant to minocycline (or the phase two/three antibiotics).
"Of course, as I have said so many times, bacteriostatics are unlikely to promote resistant species, as all species, even resistant ones, succumb to them when given for long enough periods. For example, minocycline, very widely over-prescribed for teenage acne, was released in 1968. In nearly 40 years there have been no significant species which have built resistance to it. There is one known major resistant SNP, but those microbes are still susceptible, just less so.
But bacteria may exist at the outset that are already resistant to minocycline. Delaying progress to phase two (the addition of a synergistic antibiotic) may allow tissues newly cleared of pathogens to become populated by these resistant bacteria." ..Trevor..
Low antibiotic doses reduce chance of resistant bacteria developing
The low doses at which phase two and three antibiotics are used also reduce the chance of bacterial resistance. But keep in mind that you are already infected with bacteria that have developed without cell walls to resist the standard antibiotics. It is these tiny, intra-phagocytic bacteria that are causing your problem. The antibiotics on the MP have been carefully chosen for their effectiveness against these bacteria.
How MP antibiotics are chosen
In simplistic language, we use only bacteriostatic antibiotics, and not the bactericidal ones with which your doctor will be most familiar.
The antibiotics in the MP are carefully designed to inhibit any protein transcription which uses the bacterial 30S ribonucleic acid (RNA) and 50S ribonucleic acid mediums. The molecular biology clearly shows that the 50S inhibitors are no more likely to engender microbial resistance at low doses, than at doses above the minimum inhibitory concentration (MIC).
One of the phase three antibiotics is an antimetabolite antibacterial, and inhibits production of the DHFR substrate from which the bacteria make their DNA (the nucleic acids).
CWD bacteria are already antibiotic resistant
The MP is being used against antibiotic-resistant bacteria already in your immune system. The antibiotics have been chosen so as to minimize (essentially eliminate) the likelihood that any additional resistant strains will be formed (that is, any more strains in addition to the resistant strains you are fighting with the MP).
Long-term treatment
It doesn't matter how long it takes. You have started on a lengthy journey, and the extra pain of speeding beyond a comfortable pace will not yield a comparable reduction in the length of the journey.
Antibiotic to use for emergency treatment of acute antibiotic-resistant infection
"One of the things we have planned carefully is to leave available to your Doc a key antibiotic from each class of 'macrolide' and 'tetracycline' which he/she can use for emergency infections. The macrolide is Ketek, the tetracyline is Tigecycline. Both are new, 3rd generation antibiotics with wide spectrum which Doc will be happy to use in an emergency. The MP exposes you to neither, so that if any resistance builds, both classes of abx are still available to Doc. You can point this out to him/her on your next visit." ..Trevor..
Update: Ketek has recently been linked to liver failure. Tigecycline is given intravenously. Neither of these antibiotics are recommended for routine use. They are held in reserve for use when all other antibiotics have been found ineffective.
The topic of antibiotic resistance was covered in Dr. Marshall's Plenary session presentation at our Chicago conference. DVDs.
"I have no intellectual concerns about spending 4-5 years on medications in order to reverse disease symptoms that had manifested over such a longer period of time, especially since I know how slowly L-form bacteria grow and how they can become dormant for periods of time.
I also feel there are simply no adverse reactions or negative side effects that I need to worry about while taking the medications. It's an extremely safe approach. Personally, I believe overtreating this condition is preferable than undertreating as the side effects of both antibiotics and Benicar are so minimal compared to the risk of recurrence." ~Greg Blaney, M.D.
See also:
How long does the MP take?
Why does the MP take so long?
Cell Wall Deficient Bacteria and the Marshall Protocol
Last edited on Thu Mar 13th, 2008 22:54 by
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